The evolution of Ion semiconductor sequencing has enabled researchers to
take advantage of increased throughput, higher accuracy, and longer
reads to produce rapid and accurate sequencing of microbes with
streamlined sample preparation and a simple and optimized data analysis
workflow. In addition, the Ion PGM™ System has been critical for
facilitating a rapid response during disease surveillance, investigating
outbreaks, and determining disease etiology.* Downstream of microbial
sequencing, data analysis methods include de novo and reference-guided
assembly and multi-locus sequence typing (MLST) for bacterial
identification tests or typing of microbial strains.
Microbial Sequencing Application Notes, Literature and Publications
Application Notes and Literature
- Microbial Solutions Brochure
- 16s rRNA Gene Sequencing on the Ion PGM™ System application note
- Discover how German scientists leveraged the Ion PGM™ Sequencer to
get answers when faced with a serious public health outbreak (shiga
toxin-producing E. coli outbreak in northern Germany)
- The Ion PGM™ System, with 400-base read length chemistry, enables routine high-quality de novo assembly of small genomes
- Ion PGM™ System and PathAmp™ FluA Reagents—Influenza A whole-genome sequencing
