Since its launch in 2012, Ion AmpliSeq targeted sequencing technology
has seen broad global adoption and resulted in the publication of
greater than 140 peer-reviewed publications. Applications span such
studies as investigating phenovariance in mice1, assessing gene copy
number alterations2, and defining genetic changes associated with lung
cancer3 research.
Researchers are not only using Ion AmpliSeq technology for less
challenging research samples where available sample quantity and quality
are not limiting, such as cell culture or fresh-frozen tissues, but
also seeing tremendous success with challenging sample types, such as
formalin-fixed paraffin-embedded (FFPE) tissue, achieved samples from
fine needle aspirates, and cell-free DNA extracted from blood (cfDNA).
Analysis of FFPE tumor samples
Formalin-fixed paraffin-embedded (FFPE) samples are challenging to work
with. Dr. Nicole Pfarr discubrsses her experience with Ion AmpliSeq
Panels on the Ion PGM System. (They currently use eight panels, both
standard and custom).
Content for all—Ion AmpliSeq Panels
From off-the-shelf pre-designed panels to fully customized panels of
your own design, Ion AmpliSeq Panels is designed to meet the needs of
any targeted sequencing research application. Not working with human
samples? Not a problem. Our Ion AmpliSeq™ Designer tool offers the
ability to design custom panels from 12 predefined genomes, or your own
reference genome by uploading a reference file.
