Tuesday, May 24, 2016

Understanding PathoGenetix to Present DNA Stretching Technology



PathoGenetix, Inc., a commercial-stage developer of an automated system for rapid bacterial identification, has been invited to present new research at the 2014 American Physical Society (APS) March Meeting next week in Denver, Colorado, demonstrating the integration of multiple mechanisms in its proprietary microfluidic funnels which enables optimal stretching and scanning of large DNA molecules for rapid analysis and identification of bacteria. Entitled “High-throughput DNA Stretching in Continuous Elongational Flow for Genome Sequence Scanning,” the presentation adds to the growing body of research demonstrating and detailing the company’s Genome Sequence Scanning™ (GSS™) technology, which enables rapid and reliable identification and strain typing of bacterial pathogens. The APS Physics March Meeting is expected to draw close to 10,000 physicists, scientists and students this year, with more than 600 sessions describing research from industry, universities and major laboratories from around the world.


The GSS technology has broad applicability in food safety, industrial microbiology, public health and research, and will be available in the RESOLUTION™ Microbial Genotyping System in 2014 for use in food safety testing and foodborne illness outbreak investigations. Because Genome Sequence Scanning is culture independent, and fully automated from sample preparation to final report, the technology greatly reduces the time, complexity and skill required when compared to other molecular and next generation sequencing (NGS) identification approaches. The strain-type information provided by GSS is comparable to pulsed field gel electrophoresis (PFGE), the current standard for pathogen typing in foodborne outbreak investigation and response. As a result, GSS offers a powerful new tool for epidemiological investigations and outbreak monitoring in hospital and public health labs monitoring foodborne outbreaks, and for food safety testing in the food industry.